Review On Nanoparticle : Nano Vehicles For Anticancer Drugs
Year: 2024
Type: article
Abstract: The Development of nanoparticles based drug delivery systems has emerged as a promising stratergy in the fight against cancer. These nano vehicles offer several advantages over traditional chemotherapy, including targeted drug delivery reduces side effect and improved therapeautic efficacy. These various explores the various type of nano particle used for anticancer drug delivery such as liposomes, dendrimers, polymeric nano particle Their mechanism of action including enhanced permeability and retention effect, Active targetting via ligand receptor interactions and stimuli responsive release. We also discuss the current state of clinical trials and regulatory challenges faced in the commercialization or nanoparticles based therapies. Comprehensivers analysis of recent advancements and ongoing research. This review highlights the potentials of nanoparticles to revolutionize cancer treatment and underscores the need for further studies to optimize their design and application. Nanoparticles have emerged as a promising platform for the delivery of anticancer drugs, offering targeted therapy with enhanced efficacy and reduced side effects. This review explores the various types of nanoparticles utilized as nano vehicles, including liposomes, dendrimers, polymeric nanoparticles, and metallic nanoparticles. We examine their physicochemical properties, drug loading capabilities, and mechanisms of drug release. Key advancements in nanotechnology that facilitate tumor- specific targeting through passive and active mechanisms are discussed. The review also addresses the current challenges in nanoparticle drug delivery, such as stability, biocompatibility, and the potential for clinical translation. Case studies of successful nanoparticle-based anticancer therapies are highlighted to underscore their therapeutic potential. Future perspectives on the integration of personalized medicine and nanotechnology for cancer treatment are also provided.
Author: Pagar Namrata*1, Nikam Harshada2
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W6893073146
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