Work

N-nitrosodimethylamine and N-nitrosodiethylamine Induced Hepatic Preneoplasia in Turkey Embryos

Year: 2024

Type: article

Abstract: The toxic and carcinogenic effects induced in ovo by N-nitrosodimethylamine (NDMA) and N-nitro-sodiethylamine (NDEA) in turkey embryos have been examined by means of pathoanatomical and histopatho-logical methods. The obtained results indicate that both compounds induce preneoplastic hepatic alterations. The spectrum of macroscopic and microscopic lesions identified in carcinogen treated embryos has been pre-sented and the potential use of avian embryos as an inexpensive and reliable model system for studies on the hepatocarcinogenesis has been discussed.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.14270864

Author: Nikolov, Branimir

Institution: Medical University Pleven

Language: English

Topic: Carcinogens and Genotoxicity Assessment

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6893123100