Core Endocrine Models I: A Graphic Causality System for Teaching Pancreatic and Adrenal Regulation – Dr Mihăilă Graphic System®
Year: 2025
Type: article
Abstract: This work extends the Graphic System for Teaching Physiological Causality to endocrinology, providing a standardized set of visual models for teaching hormonal regulation. Designed as a classroom-ready resource, it distills complex endocrine pathways—from glucose homeostasis to hypothalamic-pituitary axes—into intuitive radial diagrams that map causal relationships without theoretical jargon. Each figure follows three core rules: (1) parameters as bidirectional axes, (2) directional vectors for causal relationships, and (3) text boxes linked to the core construct via arrows for key pathological states. Ranging from basic (two-axis) to comprehensive (multi-axis and loop integrations), these diagrams offer a progressive learning scaffold to help students recognize regulatory patterns across endocrine systems. Building on the framework’s prior construction in physiology, this adaptation underscores its versatility as a domain-agnostic teaching tool. Methodology Notice: All diagrams in this manuscript were created using the Dr Mihăilă Graphic System®, a standardized visual method for transforming causal relationships into intuitive geometric models (multi‑axis structures and circular‑arc feedback systems). This graphical methodology has been fully detailed in our foundational work and is applied here to the specific domain addressed in this manuscript. Trademark Notice: Dr Mihăilă Graphic System® is an officially registered trademark under the European Union Intellectual Property Office (EUIPO). Public registration record: EUIPO - eSearch Keywords: endocrinology education, visual teaching tools, causal diagrams, hormonal feedback, medical pedagogy, radial graph models, clinical endocrinology To review the entire integrated roadmap of the project, explore the author's independent open-science philosophy, and navigate the cultural birthplace of this framework, visit the central ecosystem hub: Author Central Science-Art Context: Dr Mihăilă’s hand drawings inspired a parallel artistic exploration, Composition Purple 2023, by Angelica Mirela Pagu (member of UAPR Iaşi, Romania: Angelica Mirela PAGU - Uniunea Artistilor Plastici). This independent artwork: - Has been curated and featured on page 84 of The UAPR Iasi Yearbook Album 2023 (uapr-iasi-anuar-2023.pdf), - Was specifically commissioned as the cover for the monograph (Mihăilă 2023b) referenced herein, and - Is part of Dr Mihăilă’s Science-Art Certification Program. Note: This work is part of the Core Models in Physiology system, which has been downloaded over 9,500 times (and counting) by educators and students worldwide. The System's Foundation: · Built exclusively on established medical literature. · Designed as a complementary visual framework to traditional textbooks. Its Unique Power: · Provides a unified graphical language for causality and feedback. · Scalable and consistent across all physiological systems. · Proves its universal power by modeling diverse adaptive systems (from physiology to ecology) with the same core rules. Explore the full Core Models Collection New Core Models currently under construction! New Release: Standardized Core Models of Musculoskeletal Adaptation and Overuse Injury: A Didactic Framework Using the Dr Mihăilă Graphic System® https://doi.org/10.5281/zenodo.20847724 [Personally curated as the most conceptual manuscript of the entire series] All titles listed below are developed exclusively under the Dr Mihăilă Graphic System® didactic framework. [Dr Mihăilă Graphic System®] A Graphic System for Teaching Physiological Causality and Beyond. Rules and Core Model Collection https://doi.org/10.5281/zenodo.15476147 [Foundational Manuscript] This work is published under CC BY-NC-ND 4.0. license and discoverable also on: - OER Commons (A Graphic System for Teaching Physiological Causality and Beyond. Rules and Core Model Collection | OER Commons), - Share My Lesson (Robert Ioan Mihaila | Share My Lesson), and - MERLOT (Robert Ioan Mihӑilӑ (Member Profile)) digital libraries as a curated and catalogued resource. - BASE BASE (Bielefeld Academic Search Engine): Hit List Core Endocrine Models I: A Graphic Causality System for Teaching Pancreatic and Adrenal Regulation https://doi.org/10.5281/zenodo.15352067 This work is published under CC BY-NC-ND 4.0. license and discoverable also on: - OER Commons (Core Endocrine Models I: A Graphic Causality System for Teaching Pancreatic and Adrenal Regulation | OER Commons), - Share My Lesson (Robert Ioan Mihaila | Share My Lesson), and - MERLOT (Robert Ioan Mihӑilӑ (Member Profile)) digital libraries as a curated and catalogued resource. - BASE BASE (Bielefeld Academic Search Engine): Hit List Core Endocrine Models II: A Graphic Causality System for Hierarchical Axes, Multi-Loop Integration and Clinical Pattern Recognition https://doi.org/10.5281/zenodo.15698563 This work is published under “All rights reserved” and discoverable also on: - MERLOT (Robert Ioan Mihӑilӑ (Member Profile)) digital library as a curated and catalogued resource. - BASE BASE (Bielefeld Academic Search Engine): Hit List Core Models in Gastrointestinal Physiology: A Graphic Causality System Approachhttps://doi.org/10.5281/zenodo.15831259 This work is published under CC BY-NC-ND 4.0. license and discoverable also on: - OER Commons (Core Models in Gastrointestinal Physiology: A Graphic Causality System Approach | OER Commons), - Share My Lesson (Robert Ioan Mihaila | Share My Lesson), and - MERLOT (Robert Ioan Mihӑilӑ (Member Profile)) digital libraries as a curated and catalogued resource. - BASE BASE (Bielefeld Academic Search Engine): Hit List Pressure-Flow Modeling: A Unified Causal Framework for Cardiovascular and Renal Homeostasis. Core Models from Baroreceptor Reflex to Glomerular Hemodynamics https://doi.org/10.5281/zenodo.17143368 This work is published under “All rights reserved” and discoverable also on: - MERLOT (Robert Ioan Mihӑilӑ (Member Profile)) digital library as a curated and catalogued resource. - BASE BASE (Bielefeld Academic Search Engine): Hit List Economic Homeostasis: A Universal Causal Framework for Stability, from Physiological to Economic Systems https://doi.org/10.5281/zenodo.17476317 This work is published under “All rights reserved” and discoverable also on: MERLOT (Robert Ioan Mihӑilӑ (Member Profile)) digital library as a curated and catalogued resource. Core Models: One Code to Rule Them All! How the Same Loops Govern Your Body, Nature, and the Marketplace https://doi.org/10.5281/zenodo.17562888 This work is published under “All rights reserved” and discoverable also on: MERLOT (Robert Ioan Mihӑilӑ (Member Profile)) digital library as a curated and catalogued resource. Core Models: The Secret Code of Vicious and Virtuous Cycles! How Small Actions Create Big Successes or Big Problems https://doi.org/10.5281/zenodo.17671018 This work is published under “All rights reserved” and discoverable also on: MERLOT (Robert Ioan Mihӑilӑ (Member Profile)) digital library as a curated and catalogued resource. Standardized Core Models of Musculoskeletal Adaptation and Overuse Injury: A Didactic Framework Using the Dr Mihăilă Graphic System® https://doi.org/10.5281/zenodo.20847724 [Anchor Manuscript] This work is published under “All rights reserved” and discoverable also on: MERLOT (Robert Ioan Mihӑilӑ (Member Profile)) digital library as a curated and catalogued resource.
Author: Mihăilă, Robert Ioan
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W6893148822
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