Work

Gradient of Modifier Versus Gradients of Temperature and Pressure in Hplc

Year: 2025

Type: article

Abstract: The presentation describes the effects of temperature and pressure on retention in the HPLC chromatography process. The possibilities of using temperature and pressure gradients as factors enabling the controlling of the retention process and possible instrumentation solutions were presented. A two-dimensional mathematical model of a chromatographic column was shown, taking into account momentum, mass and heat balances, the numerical solution of which allows predicting the column's behavior under temperature and pressure gradients.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.14995485

Authors: Chutkowski, Marcin, Przywara, Mateusz, Kaczmarski, Krzysztof

Institution: Rzeszów University of Technology

Language: English

Topic: Analytical Chemistry and Chromatography

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

OpenAlex ID: W6893176732

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