Work

Prevalence and management patterns of type 2 diabetes associated cardiovascular complications

Year: 2025

Type: article

Abstract: The present investigation was targeted to examine the morbidity of cardiovascular complications in patients with type 2 diabetes mellitus and also the trends in the management of complications in Uzbekistan. This analytic cross-sectional study was conducted among 1200 patients with type 2 diabetes with a mean age of 58.4 years (range: 45-70 years) of the year 2018-2023 in the medical centers of Tashkent, Samarkand and Bukhara. Data were collected through a review of medical records, clinical evaluation and standardized questionnaires. 45.2% of the patients had ≥ 1 cardiovascular complications based on the findings. The most common complications were ischemic heart disease (28.1%), hypertension (20.4%), heart failure (15.3%) and cerebrovascular accidents (8%). Of the risk factors, obesity (67.5%), dyslipidemia (58.9%) and uncontrolled blood sugar levels (mean HbA1c: 8.6%) were the most common causes for these complications to occur. The management pattern indicated that 74.8% of the patients were on metformin, 60.3% were on insulin, and 45.6% were on statins. But only 39.7% of the patients achieved the target of treatment for HbA1c <7%. For blood pressure management, 51.2% of the patients were on antihypertensive therapy and 35.4% had achieved LDL-C <100 mg/dL. Lifestyle modification in the form of regular exercise (30.1%) and healthy diet (24.8%) was reported at a low rate. The results show a high rate of cardiovascular complications among Uzbek diabetic patients and a large disparity in optimal control of these complications. Increasing access to combination treatments, patient education, and intensifying cardiovascular screening programs among these patients are advised.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.15363879

Authors: Amonova Zakhro Kakhramonovna, Hamidova Feruza Karimovna, N. Esanmurodova, Abdullayev Dadaxon, Boboev Behzod Muminjon ugli, Bobur Raximov, Yuldasheva Zarofat Igamberdiyevna, Ro'zaliyev Komiljon Nosirovich

Institutions: Samarkand State Medical Institute, Bukhara State Medical Institute named after Abu Ali ibn Sino, Tashkent Institute of Irrigation and Agricultural Mechanization Engineers, Baku Eurasian University, Urgench State University, Tashkent Medical Academy, Mamun University

Language: English

Topic: Diabetes Treatment and Management

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6893193329

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