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A Study of QT Dispersion and Its Correlation with Ventricular Arrhythmias in Acute Myocardial Infarction

Year: 2024
Type: article
Abstract: Background: Coronary artery disease is the leading cause of mortality worldwide. Atherosclerosis is the most common cause of luminal narrowing in coronary artery disease however; multiple non-atherosclerotic cause account for 4-7% of cause acute MI. From the start of the Q wave to the finish of the T wave, the QT interval is measured in seconds. The difference between the maximum and least QT interval is used to quantify QT dispersion. It is thought that QTd is a measure of cardiac inhomogeneity that lowers a person’s threshold for ventricular arrhythmias. Therefore, the likelihood of developing arrhythmias increases with the QTd. Our study’s objectives are to determine how QT dispersion is measured in acute myocardial infarction, evaluate the relationship between QT dispersion and the infarct site, and investigate the relationship between QT dispersion, ventricular arrhythmias, and acute myocardial infarction mortality. Materials and Methods: 86 Patients admitted in medicine ICCU of Kanyakumari government medical college diagnosed to have acute myocardial infarction fulfilling the inclusion and exclusion criteria are included in this study group. Results: Mean QTc interval for arrhythmia cases are 397.4 and 387.1 for non- arrhythmias. This difference is statistically significant. P value is 0.003. Mean QTc dispersion for arrhythmia cases are 89.26 and 63.3 for non-arrhythmias. This difference is highly statistically significant. AMI is associated with changes in the electrophysiological properties of the heart. By means of assessing QT dispersion from the surface electrocardiogram there is convincing evidence that in AMI, inhomogeneity in ventricular repolarization is augmented. Conclusion: Mean QT dispersion is significantly increased after Acute Myocardial Infarction. With time, QT dispersion dynamically decreases. Individuals with ventricular tachycardia and ventricular fibrillation had larger mean QT dispersion values than individuals with acute myocardial infarction who do not have these arrhythmias. QT dispersion changes dynamically and could be a non-invasive indicator of vulnerability to malignant ventricular arrhythmias.
Authors: B. Thanalakshmi, Jayaram Kosalram, L. Sivaranchani, Vidhya K.
Language: English
Field: Medicine
Open Access status: green
OpenAlex ID: W6893201092
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