Work

ntRoot: Scalable Ancestry Predictions from Genome Sequencing Data

Year: 2024

Type: article

Abstract: We present ntRoot, an alignment-free and computationally lightweight framework for inferring human super-population-level global and local ancestry from whole genome assemblies or raw sequencing data types, and demonstrate its utility on over 300, Simon Genome Diversity Project and 1000 Genomes Project datasets. ntRoot is available from https://github.com/bcgsc/ntRoot. A preprint describing the technology is accessible at https://doi.org/10.1101/2024.03.26.586646

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.13844276

Author: Warren, Rene

Institutions: Provincial Health Services Authority, Canada's Michael Smith Genome Sciences Centre

Language: English

Topic: Forensic and Genetic Research

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: Canadian Institutes of Health Research

Award: Assembly and annotation of genomes, transcriptomes, and metagenomes