Review on the Formulation and Evaluation of Curcumin Gel
Year: 2025
Type: article
Abstract: Curcumin, a bioactive polyphenolic compound extracted from Curcuma longa (turmeric), has gained significant attention in recent years for its diverse therapeutic properties, including antioxidant, anti-inflammatory, antimicrobial, and anticancer activities. However, its clinical application is hindered by poor aqueous solubility, low stability in physiological conditions, and limited systemic bioavailability when administered orally. To overcome these challenges, topical drug delivery systems, especially gel formulations, have emerged as effective alternatives for local and site-specific delivery of curcumin. This review comprehensively discusses the rationale for curcumin gel formulation, selection of appropriate excipients, methods of preparation, evaluation parameters, and therapeutic applications. Emphasis is placed on improving drug stability, release behavior, and pharmacological efficacy. The review concludes that curcumin gel is a promising herbal formulation with potential use in treating various inflammatory, infectious, and dermatological conditions.
Author: Harsh Choudhary*, Sacchidananda Yadav, Dr. Kshitij Agarwal
Language: English
Subfield: Pharmaceutical Science
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W6893234515
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