Fluid Exchange Condition in Hypertension: a Review of Physiological Mechanisms and Clinical Implications
Year: 2025
Type: article
Abstract: Hypertension is a chronic condition characterized by elevated blood pressure, often accompanied by disturbances in fluid exchange mechanisms. This article explores the physiological processes involved in fluid regulation, focusing on capillary filtration, vascular permeability, and sodium balance. Dysfunctions in the renin-angiotensin-aldosterone system (RAAS) can lead to extracellular fluid accumulation, endothelial dysfunction, and impaired lymphatic drainage, contributing to edema and circulatory instability. Understanding these mechanisms is essential for effective hypertension management and therapeutic interventions. Current treatments targeting fluid balance, including diuretics and RAAS modulators, provide promising strategies for mitigating fluid-related complications. Further research is needed to refine precision medicine approaches for hypertension patients with altered fluid dynamics.
Authors: Yormatov, Shaxzodbek, Alyavi Anis Lutfullayevich
Institution: Tashkent Medical Academy
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W6893239673
FWCI:
Cites:
Cited by:
Related to: