UV-vis Spectrophotometric Method for Estimation of Voriconazole in Tablet
Year: 2025
Type: article
Abstract: A simple, specific and sensitive UV-vis spectrophotometric method has been developed using buffer pH 1.2 as solvent for the estimation of voriconazole in tablet. The drug shows maximum absorbance at 256 nm. The technique demonstrated a linear response within a concentration range of 10-50 μg/ml, achieving a correlation coefficient of 0.9999. The precision study shows the % RSD was 0.566. Recovery studies showed accuracy of 101%. The LOD and LOQ found to be 1.57 µg/mL and 4.77 µg/mL respectively. The validation parameter outcomes showed that the method demonstrated accuracy, precision, reproducibility, sensitivity. Therefore, this technique is beneficial for regular quality control assessments for determining voriconazole in solid dosage forms.
Author: Priyanka Bidave*, Mallinath Kalshetti
Language: English
Subfield: Analytical Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W6893344552
FWCI:
Cites:
Cited by:
Related to: