Advancing Analytical Insights: A review Estimation Techniques for Acebrophylline and Erdostaine
Year: 2025
Type: article
Abstract: The present review provides a comprehensive overview of the various analytical techniques used for the estimation of Acebrophylline and Erdosteine, two therapeutic agents primarily used in the management of respiratory disorders. Acebrophylline, a bronchodilator and anti-inflammatory agent, and Erdosteine, a mucolytic, have gained prominence in respiratory care. Accurate quantification of these drugs in bulk, pharmaceutical formulations, and biological matrices is crucial for quality control and pharmacokinetic studies. This review explores diverse analytical methods, including spectroscopic techniques (UV) chromatographic methods (HPLC, UPLC, TLC), and, highlighting their advantages, limitations, and applications. Special emphasis is placed on recent advancements such as green analytical chemistry approaches and stability-indicating methods. The review also discusses method validation parameters in accordance with ICH guidelines, including precision, accuracy, sensitivity, and specificity. This paper aims to serve as a reference guide for researchers and pharmaceutical analysts in developing robust methods for the routine analysis of Acebrophylline and Erdosteine.
Author: Priya Vadariya*1, Hiral Popaniya2, Dr. Payal Vaja3, Smruti Sankhant4, Mihir Makwana5
Language: English
Subfield: Analytical Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W6893357621
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