Comprehensive Insight into Tablet Formulations: Types, Manufacturing Techniques, and Evaluation Standards
Year: 2025
Type: article
Abstract: Tablets are a commonly used solid dosage form prepared through compression methods. They are essential for treating various medical conditions and are preferred by patients due to their convenience compared to other dosage forms. Tablets are cost-effective, easy to administer, and ensure precise dose delivery for therapeutic purposes. Table manufacturing techniques include wet granulation, dry granulation, and direct compression. These involve mixing active pharmaceutical ingredients (API) with excipients, blending, granulating, or direct compression using a tablet punching machine. Innovations in solid dosage forms, such as fast-dissolving tablets, ensure rapid drug absorption into systemic circulation for desired effects. Coating methods are used to mask unpleasant odours or tastes and to control drug release at targeted sites. Various parameters, including dissolution, disintegration, friability, and hardness, are evaluated to assess tablet absorption, efficacy, and toxicity. However, defects such as capping, picking, sticking, mottling, and weight variations can occur during manufacturing.
Author: Sanket Khedkar*, Dr. Nikita Parage
Language: English
Subfield: Computational Mechanics
Field: Engineering
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W6893390994
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