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Analysis of bioactive compounds, cytotoxic potential, and TLC profile of fruits of Chloroxylon swietenia DC. (Rutaceae)

Year: 2025

Type: article

Abstract: Chloroxylon swietenia DC. (Rutaceae) is a plant species known for its medicinal properties, with its fruits being used in traditional medicine for various ailments. This study aimed to investigate the presence of metabolically active compounds, cytotoxic activity, and TLC profile of the fruits of C. swietenia. Phytochemical analysis revealed the presence of various bioactive compounds, including tannins, saponins, reducing sugars, and alkaloids. The cytotoxic potential of the fruit extract was evaluated using the Brine shrimp assay, which showed significant cytotoxic activity. TLC profiling was used to identify and characterise the bioactive compounds present in the fruit extract. The results of this study provide scientific evidence for the traditional use of C. swietenia fruits and highlight their potential as a source of bioactive compounds with cytotoxic properties. Further research is warranted to isolate and characterise the bioactive compounds responsible for the observed cytotoxic activity.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.16825269

Authors: Behera, Banshidhar, Singh, Gajender, Majhi, Saraswati, Tambe, Satish Sampatrao, Rout, Subhalakshmi, Mudalkar, Shalini

Institutions: Rama Devi Women's University, Loknete Vyankatrao Hiray Arts, Science and Commerce College, Ambika Prasad Research Foundation

Language: English

Topic: Phytochemical Studies and Bioactivities

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6893416307

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