Work

How to stop a gene drive

Year: 2025

Type: article

Abstract: This living literature review examines emergency countermeasures developed to halt or reverse gene drive activity if intrinsic safeguards fail. It focuses on two main categories: secondary releases of engineered organisms and non-heritable targeted inhibitors. The article assesses the strengths, limitations, and research gaps of each strategy, and includes a visual map of the literature to help track emerging trends and connections across studies. As a living literature review, this article will be updated with new modeling insights and methodologies as they become available.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.16566317

Author: Moronta Barrios, Felix

Institutions: International Centre for Genetic Engineering and Biotechnology, International Centre for Genetic Engineering and Biotechnology, International Centre for Genetic Engineering and Biotechnology

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W6893497716

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