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Appiah et al. Chronic Intermittent Hypoxia and Ovariectomy Exert Independent and Region-specific Effects on ΔFosB Expression in Central Autonomic Regions and Increase Blood Pressure in Female Rats

Year: 2025
Type: article
Abstract: We investigated the effects of ovarian hormone depletion and chronic intermittent hypoxia (CIH) on blood pressure and ΔFosB staining in central autonomic regions. Our findings indicate that ovariectomy (OVX) and CIH have independent effects on blood pressure and produce region-specific changes in ΔFosB staining in the central autonomic regions associated with hypertension. This suggests that the effects of CIH and OVX on ΔFosB staining and hypertension are not additive.
Source: Figshare
Language: English
Subfield: Physiology
Field: Medicine
Open Access status: green
OpenAlex ID: W6902119223
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