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Additional file 1 of Long-term exposure to multiple air pollutants and multi-level socioeconomic status: joint effects on age-related macular degeneration, subsequent ocular comorbidity, and death in middle-aged and older adults

Year: 2025

Type: article

Abstract: Additional file 1: Supplement Method 1 Assessment of socioeconomic status. Supplement Method 2 Statistical method used for estimating the life expectancy. Table S1 Correlation analysis of air pollutants. Table S2 Factor loadings from principal components analysis to create APS1. Table S3 Definition of each component of a healthy diet score. Table S4 Ascertainment of outcome. Table S5 Baseline characteristics of the participants by APS1. Table S6 Baseline characteristics of the participants by APS2. Table S7 Hazard ratios and 95% confidence interval for the air pollution scores with incident AMD. Table S8 Hazard ratios and 95% confidence interval for the air pollution scores with incident OCMD after AMD diagnosis. Table S9 Hazard ratios and 95% confidence interval for the air pollution scores with all-cause mortality. Table S10 Hazard ratios and 95% confidence interval for the socioeconomic status with incident AMD. Table S11 Hazard ratios and 95% confidence interval for the socioeconomic status with incident OCMD after AMD diagnosis. Table S12 Hazard ratios and 95% confidence interval for the socioeconomic status with all-cause mortality. Table S13 Associations of APS1 and socioeconomic status with transitions. Table S14 Associations of APS2 and socioeconomic status with transitions. Table S15 Associations of APS1 and socioeconomic status with transitions. Table S16 Associations of APS2 and socioeconomic status with transitions. Table S17 Associations of APS1 and socioeconomic status with transitions. Table S18 Associations of APS2 and socioeconomic status with transitions. Table S19 Associations of APS1 and socioeconomic status with transitions. Table S20 Associations of APS2 and socioeconomic status with transitions. Table S21 Associations of APS1 and socioeconomic status with transitions. Table S22 Associations of APS2 and socioeconomic status with transitions. Table S23 Associations of APS1 and socioeconomic status with transitions. Table S24 Associations of APS2 and socioeconomic status with transitions. Table S25 Analyses on additive and multiplicative interactions between APS1 and SES with incident AMD. Table S26 Analyses on additive and multiplicative interactions between APS2 and SES with incident AMD. Fig. S1 Flowchart of participant enrollment. Fig. S2 Dose–response associations between air pollutants and incident AMD. Fig. S3 Dose–response associations between air pollutants and incident OCMD after AMD diagnosis. Fig. S4 Dose–response associations between air pollutants and all-cause mortality. Fig. S5 Joint associations of APS1 and socioeconomic status with incident OCMD after AMD diagnosis. Fig. S6 Joint associations of APS2 and socioeconomic status with incident OCMD after AMD diagnosis. Fig. S7 Joint associations of APS1 and socioeconomic status with all-cause mortality. Fig. S8 Joint associations of APS2 and socioeconomic status with all-cause mortality. Fig. S9 Joint associations of APS1 and area-level SESwith AMD. Fig. S10 Joint associations of APS2 and area-level SESwith AMD. Fig. S11 Joint associations of air pollutants and AMD-PRS with incident AMD. Fig. S12 Joint associations of air pollutants and healthy lifestyle with incident AMD.

Source: Figshare

DOI: 10.6084/m9.figshare.29454034

Authors: Yang, Yang, Chen, Liangkai, Liu, Qichen, Mu, Min, Huang, Jing, Zhang, Guangming, Song, Qianqian