Metal-free CH-functionalization of trisubstituted alkenes with pyridinium ylides: Development of the concept
Year: 2025
Type: article
Abstract: An effective concept for metal-free CH-functionalization of trisubstituted alkenes with pyridinium ylides proceeding via tandem Michael addition/elimination of a pyridine molecule has been proposed. A new series of CH-functionalization products were synthesized via the reaction of in situ generated pyridinium ylides with thiazolones and selenazolones containing an exocyclic double bond substituted by an alkoxycarbonyl group in moderate to excellent yields and high diastereoselectivity.
Source: Figshare
Authors: Streltsov, Andrey А., Izmest’ev, Alexei N., Kolotyrkina, Natalya G., Kravchenko, Angelina N., Gazieva, Galina A.
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W6902274067
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