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Additional file 1 of Microbially produced imidazole propionate impairs prostate cancer progression through PDZK1

Year: 2025

Type: article

Abstract: Supplementary Material 1: Figure S1 The effect of IMP on different prostate cells. A Safety assay of IMP on normal prostate cancer cells RWPE-1 cells. B Histogram depicting cell colony counts following stimulation with IMP for PC3 and DU145 cells. C EdU staining plots of DU145 cells after IMP stimulation. Scale bar, 200 μm. D Histogram showing EdU detection results for PC3 and DU145 cells. E Western blot of PDZK1 in tumour and normal tissues. F Apoptosis assay of PC3 and DU145 after 48h of treatment with the corresponding concentrations of IMP. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001; ns, not significant.

Source: Figshare

DOI: 10.6084/m9.figshare.28226048

Authors: Jin, Shengkai, Zhou, Yuhua, Lv, Jing, Lu, Yichen, Zhang, Yuwei, Li, Menglu, Feng, Ninghan

Institutions: Jiangnan University, Wuxi No.2 People's Hospital, Nanjing Medical University, Nantong University

Language: English

Topic: Prostate Cancer Treatment and Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6902287341

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