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Additional file 5 of Histamine N-methyltransferase (HNMT) as a potential auxiliary biomarker for predicting adaptability to anti-HER2 drug treatment in breast cancer patients

Year: 2025

Type: article

Abstract: Additional file 5: Fig. S5 H- and L-cell phenotypes visualized by IHC staining in BC tumor tissue. (A-C) H&E , HER2 IHC, and HNMT/HER2 dual IHC staining of HER2+ BC tumor tissues (A), PDX tumors (B), and HNMT-overexpressing TNBC cell xenograft tumors (MDA-MB-231 (top) and HCC38 (bottom)) (C). Scale bar = 20 µm.

Source: Figshare

DOI: 10.6084/m9.figshare.28180966

Authors: Cheng, Tzu-Chun, Hung, Mien-Chie, Wang, Lu-Hai, Tu, Shih-Hsin, Wu, Chih-Hsiung, Yen, Yun, Chen, Chi-Long, Whang-Peng, Jacqueline, Lee, Wen-Jui, Liao, You-Cheng, Lee, Yu-Ching, Pan, Min-Hsiung, Lin, Hui-Kuan, Tzeng, Huey-En, Guo, Peixuan, Chu, Cheng-Ying, Chen, Li-Ching, Ho, Yuan-Soon

Institutions: China Medical University, China Medical University, Asian University, Taipei Medical University, National Taiwan University, Duke University, National Chung Hsing University, Taichung Veterans General Hospital, The Ohio State University

Language: English

Topic: HER2/EGFR in Cancer Research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6902298349

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