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Additional file 1 of Assessment of chromatin remodeling of acute myeloid leukemia cells treated with gilteritinib: a case report

Year: 2025

Type: article

Abstract: Additional file 1: Fig. S1. Flow-cytometric results for CD34 + cells isolated from the blood samples before (left) and after (right) the treatment with gilteritinib. The fluorescence intensities of 7-amino-actinomycin D (7-AAD) (y-axis) and CD34 (x-axis) are shown in the dot plots. The gated region represents CD34 + and 7-AAD- leukemia blasts. Fig. S2. Motif enrichment analysis of AML cells before and after treatment. DNA-binding motifs included in the opened chromatin regions in AML cells before and after treatment with gilteritinib are shown. Listed are transcription factors known to bind the motifs.

Source: Figshare

DOI: 10.6084/m9.figshare.28729496

Authors: Mori, Jinichi, Sawada, Takahiro, Nojiri, Koki, Kanemoto, Yoshiaki, Okada, Tadashi, Kurokawa, Tomohiro, Kato, Shigeaki

Institutions: Fukushima Medical University, Jyoban Hospital of Tokiwa Foundation, Okawa Foundation for Information and Telecommunications, IRYO Sosei University

Language: English

Topic: Acute Myeloid Leukemia Research

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6902342544

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