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Plant compounds inhibit UV radiation-induced erythema in mice skin

Year: 2025
Type: article
Abstract: Phytochemicals are photoprotective compounds that prevent mutations involved in skin cancer and ageing. We studied protective activity of plant compounds against ultraviolet B (UVB) radiation induced skin erythema in albino BALB/c mice. The protective effect was quantified using narrow-band reflectance spectroscopy both in the presence and the absence of plant compounds. Among the studied compounds, five (apigenin, caffeic acid, epigallocatechin gallate (EGCG), kaempferol, and pinocembrin) inhibited UVB-induced skin erythema in mice; thus, they are promising for skin photoprotection. Erythema measurements of mice skin using narrow-band reflectance spectroscopy are valuable for the identification of photoprotective compounds.
Source: Figshare
Authors: Villamizar-Mantilla, Diego Armando, Stashenko, Elena E., Lorenzo, Jorge Luis Fuentes
Language: English
Subfield: Dermatology
Field: Medicine
Open Access status: green
OpenAlex ID: W6902420834
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