Additional file 3 of γ-Secretase modulator resistance of an aggressive Alzheimer-causing presenilin mutant can be overcome in the heterozygous patient state by a set of advanced compounds
Year: 2025
Type: article
Abstract: Supplementary Material 3: Figure S3. Dose-response analysis of BPN-15606. Dose-response curves of BPN15606 in HEK293/sw cells measured using the MSD sandwich immunoassay (n = 4–6). In the lower panel, Aβ37 and Aβ38 were excluded to enlarge the effects on Aβ40 and Aβ42. Data are presented as mean ± SEM.
Source: Figshare
Authors: Trambauer, Johannes, Sarmiento, Rosa Maria Rodriguez, Garringer, Holly J., Salbaum, Katja, Pedro, Liliana D., Crusius, Dennis, Vidal, Ruben, Ghetti, Bernardino, Paquet, Dominik, Baumann, Karlheinz, Lindemann, Lothar, Steiner, Harald
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W6902428593
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