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Additional file 5 of Myogenic IGFBP5 levels in rhabdomyosarcoma are nourished by mesenchymal stromal cells and regulate growth arrest and apoptosis

Year: 2025

Type: article

Abstract: Additional file 5. Differentially expressed genes in the IGF1 pathway. A. IRS1 (rank 1, q-value <0.001), PIK3R1 (rank 2, q-value 0.008) and CSNK2A2 (rank 3, q-value 0.08) were differentially expressed genes comparing high versus low IGFBP5 gene expression in the Discovery RMS cohort. B. IGF1 (rank 1, q-value 0.02), IRS1 (rank 2, q-value 0.009) and MAP2K1 (rank 3, q-value <0.001) were differentially expressed genes in the Validation RMS cohort comparing high versus low IGFBP5 gene expression.

Source: Figshare

DOI: 10.6084/m9.figshare.28802087

Authors: Zhang, Yue, Katkhada, Karim, Meng, Liu Zhen, Zhao, Binbin, Tong, Shanlin, Chaabane, Wiem, Kallai, Aditi, Tobin, Nicholas P., Östman, Arne, Mega, Alessandro, Ehnman, Monika

Institutions: Karolinska Institutet, Karolinska University Hospital, University of Bergen

Language: English

Topic: Sarcoma Diagnosis and Treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6902433098

FWCI:

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