Year: 2025
Type: article
Abstract: Giant cell myocarditis (GCM) and cardiac sarcoidosis (CS) are rare, inflammatory cardiomyopathies with overlapping presentations but differing treatments and prognoses. We present a case of a middle-aged woman diagnosed initially with GCM based on clinical presentation and endomyocardial biopsy. After unexpected clinical improvement and persistent mediastinal lymphadenopathy, lymph node biopsy revealed non-necrotizing granulomas, leading to a revised diagnosis of CS. This case highlights the diagnostic challenges presented by inflammatory cardiomyopathies and the importance of reassessing initial diagnoses in the context of evolving clinical and imaging findings.
Source: CJC Open
Authors: Enklajd Marsela, Regina Lief, Konstantinos Loupasakis, Mark I. Travin, James Pullman, Agnes Colanta, Aldo Schenone, Snehal R. Patel, Daniel B. Sims, Ulrich P. Jorde, Yogita Rochlani
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,590
OpenAlex ID: W6903101431