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Malignant transformation of rectal endometriosis: a clinicopathological study and molecular analysis of 2 cases

Year: 2024

Type: article

Abstract: Endometriosis is a common disorder, while malignant transformation of endometriosis in the colon is rare. The main clinical manifestations include pelvic masses, abdominal or pelvic pain, vaginal bleeding, rectal bleeding, and intestinal obstruction. In early patients with endometriosis-related colon cancer, the most common involvement on imaging is the serosa or subserosa layer, with no mucosal lesions or minor lesions; while in advanced cases, it resembles primary colon cancer.This paper collected 2 cases of endometrioid carcinoma associated with rectal (extrinsic gonadal) endometriosis to investigate its clinicopathological features and molecular changes, and to review the relevant literature to improve the understanding of diagnostic physicians so as to avoid misdiagnosis.

Source: DOAJ (DOAJ: Directory of Open Access Journals)

DOI: 10.12173/j.issn.1004-5511.202404033

Authors: ZHANG Tianming, LI Xiaowen, FANG Na

Language: English

Topic: Endometriosis Research and Treatment

Subfield: Reproductive Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6903521771

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