Angiocentric glioma: clinical, pathomorphological and neuroradiological features of a rare epileptogenic tumor (a review and clinical case)
Year: 2024
Type: article
Abstract: Angiocentric glioma is an extremely rare low-grade neuroepithelial tumor introduced into the World Health Organization classification of tumors of the central nervous system in 2007. Microscopically, it is a cluster of monomorphic bipolar cells with a predominant diffuse growth pattern and focal perivascular aggregation of tumor cells around blood vessels, which forms a specific angiocentric pattern. Despite the fact that a little more than 100 cases of detection of angiocentric glioma have been described in the literature, a number of clinical, pathomorphological and radiological criteria specific for this tumor have been identified that are characteristic long-term epilepsy associated tumors. The article presents the experience of complex, interdisciplinary diagnosis of angiocentric glioma in a child with focal structural epilepsy and a review of the literature. It should be noted that this is the first case of describing pathomorphologically confirmed angiocentric glioma on the territory of the Russian Federation.
Authors: V. S. Khalilov, A. N. Kislyakov, O. A. Ryleva, N. A. Medvedeva, A. A. Kholin
Institutions: Pirogov Russian National Research Medical University, Children's Scientific and Clinical Center for Infectious Diseases of the Federal Medical and Biological Agency, Ministry of Health of the Russian Federation, Federal Medical-Biological Agency, Burdenko Neurosurgery Institute, Sechenov University
Language: English
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W6906423580
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