Work

Effective, durable, and safe delivery of rAAV vectors to human bone marrow-derived mesenchymal stem cells guided by pNaSS-PEGDA and pNaSS-PEGDA/TCP hydrogels

Year: 2024

Type: conference-paper

Abstract: Objectives: Human bone marrow-derived mesenchymal stromal cells (hMSCs) modified by recombinant adeno-associated virus gene vectors (rAAV) are a potent source of implantable cells in articular cartilage defects, especially when rAAV are provided via scaffolds to control their release [ref:1]. [for full text, please go to the a.m. URL]

Source: German Medical Science (German Research Foundation)

DOI: 10.3205/24dkou387

Authors: Venkatesan, Jagadeesh K., Nguyen, Tuan Ngoc, Orth, Patrick, Migonney, Veronique, Madry, Henning, Cucchiarini, Magali

Institutions: Universitätsklinikum des Saarlandes, Ceraver (France)

Language: English

Topic: Virus-based gene therapy research

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6908483448

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