Global Trends in CD4 Measurement and Immunosuppression at ART Initiation Among Children With HIV.
Type: article
Abstract: Eligibility for antiretroviral therapy is no longer based on immune criteria. In a global cohort of 97,453 children, between 2005 and 2021, we observed large declines in CD4 measurement, from 51% to 12% among <5 seconds, and from 74% to 20% among those 5-14 years of age. Lack of CD4 testing may negatively affect clinical care and surveillance of severe immune suppression.
DOI: 10.48620/87842
Authors: Patten, Gabriela, Malateste, Karen, Bolton Moore, Carolyn, Sipambo, Nosisa, Mokone, Limpho, Anderegg, Nanina, Wools-Kaloustian, Kara, Michael, Denna, Odhiambo, Francesca, Kasozi, Charles, Desmonde, Sophie, Amorissani-Folquet, Madeleine, Leroy, Valériane, Kumara Wati, Dewi, Nallusamy, Revathy, Kinikar, Aarti, Quy, Du Tuan, Yotebieng, Marcel, Ebasone, Peter Vanes, Lelo, Patricia, Pinto, Jorge, Rouzier, Vanessa, Machado, Daisy Maria, Haw, Nel Jason, Ford, Nathan
Institution: Institute of Social and Preventive Medicine
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W6910632825
Cites:
Cited by:
Related to: