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Synthesis and biological evaluation of 1,2,4-oxadiazole linked imidazopyrazine derivatives as anticancer agents

Year: 2024

Type: article

Abstract: A series of new 1,2,4-oxadiazole linked imidazopyrazines(10a-j) were synthesized and evaluated for their cytotoxic activity against various human cancer cell lines, such asMCF-7 (breast), A549 (lung), and A375 (melanoma).These compounds showed moderate to appreciable anticancer activities.Among them, compounds 10b, 10c, 10d, 10f and 10i were showed more potent activity than adriamycin

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.13825480

Author: SRILALITHA VINNAKOTA, RAMANA KUMAR KAKARLA, ANITHA NALLAMOTHU

Language: English

Topic: Synthesis and biological activity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6911731206

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