Clinical Utility of (123) I-MIBG Scintigraphy in Suspected Dementia with Lewy Bodies
Year: 2024
Type: article
Abstract: A Clinical diagnosis of Lewy Body Dementia (LBD) has low sensitivity (positive predictive values of 34% to 47%). Although Dopamine Active Transporter (DaT) brain scintigraphy is generally useful in suspected LBD, it has a diagnostic sensitivity of only 85%. A normal scan may, therefore, present a dilemma. 123I-MIBG Myocardial Scintigraphy (MIBG) may support diagnosis, but the diagnostic cut-off values are poorly defined. Here, we describe the presentation of an assessment of a patient with cognitive impairment and psychotic symptoms and discuss the role of investigations aimed at supporting the diagnosis of LBD in clinical practice.
Author: Hopwood, H
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W6911818329
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