Formulation And Evaluation of Dissolving Oral Film Containing Glutathione as Skin Lightening Agent
Year: 2025
Type: article
Abstract: “The Study on the formulation and evaluation of dissolving oral film Containing Glutathione as skin Lightening Agent. Skin Whitening treatments are now readily accessible in markets as topical, Oral or injectable Formulation Multiple experiments Demonstrated that glutathione showed Antimelanogenic effects, thus it is associated with melanin production. The Solvent casting method and formulation was done with the several Evaluation tests such as, Organoleptic Properties, thickness, Folding endurance, Drug content Uniformity, Dryness/tack test, Tensile Strength Percent elongation, tear resistance, Young's modulus, In vitro dissolution studies, contact Angle, Transparency Scanning electron microscopy, permeation studies, percentage moisture loss & Stability Study. Above studies shows that, one of the best skin-whitening strips is film. Using an oral dissolving film to deliver Medication has various benefits. ODFs are excellent dose form for infants & the elderly because they are simple to swallow and pose no choking hazard. Adverse effects reported with Intravenous glutathione injection by the FDA. To overcome the adverse effects by IV route, the oral dissolving film formulated. Global glutathione market size was over USD 195 million in 2020 is estimated to grow at over % upto 2027 owing to wide application of glutathione in numerous industries such as pharmaceutical, cosmetic, food and nutraceuticals. Reduced glutathione market size should surpass USD 200 million by 2027 & is anticipated to show growth over 7.0% CAGR upto 2027.”
Author: Kunal Rathod, Ganesh Patil, Chetan Narkhede, Lalita Patil*
Language: English
Subfield: Pharmaceutical Science
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W6911839713
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