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Optimal Endocrine Therapy for Premenopausal Women with Breast Cancer

Year: 2024

Type: article

Abstract: Hormone receptor-positive breast cancer treatment involves suppressing estrogen levels, particularly in postmenopausal women. Aromatase inhibitors (AIs) and selective estrogen receptor degraders (SERDs) are effective in postmenopausal women, but their use in premenopausal women requires additional strategies to suppress ovarian estrogen production. Ovarian function suppression (OFS) combined with AIs is a cornerstone of adjuvant endocrine therapy for high-risk premenopausal patients, significantly improving invasive disease-free survival and overall survival. A personalized and multidisciplinary approach is essential to address treatment-related side effects and ensure comprehensive care for premenopausal women with breast cancer.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.14538005

Author: Makedonskaia, Sofiia

Institution: American Association of Gynecologic Laparoscopists

Language: English

Topic: Breast Cancer Treatment Studies

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6911871532

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