A Review Article On Analytical Method Development And Method Validation Of Drug Tramadol
Year: 2024
Type: article
Abstract: Acute lymphoblastic leukemia (ALL) can affect both children and adults, with a peak incidence between ages one and four. Most cases occur in otherwise healthy individuals, with few having identifiable risk factors. The disease is characterized by chromosome abnormalities and genetic changes that affect lymphoid precursor cells.Outcomes have improved significantly for children and young adults due to tailored treatment strategies, but older adults and those with relapsed or refractory ALL still face poor prognosis. New immunotherapy options, like CAR T-cell therapy and monoclonal antibodies, are being developed to enhance treatment.ALL is part of a broader group of lymphoid cancers, and distinguishing it from other cancers involves analyzing its specific morphological, immunophenotypic, and genetic traits. Current aggressive chemotherapy regimens cure about 85-90% of children and 40-50% of adults, but results can vary based on the disease's genetic subtype and clinical features at diagnosis. Monitoring minimal residual disease is essential for assessing prognosis and optimizing treatment
Author: Zakira Chaudhary*1, Aarti Yadav2, Chainesh Shah3, Umesh Upadhyay4
Language: English
Subfield: Analytical Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W6911889083
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