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Review: Neuroprotective Effect of Herbal Extract

Year: 2024
Type: article
Abstract: One of the biggest health issues of the twenty-first century is neurodegeneration, which is the name for the state of neuronal death caused on by a long-term, degenerative disease. Neurodegenerative disorders (NDs) include epilepsy, Parkinson's, Alzheimer's, and Huntington's, pose a significant threat to global health, affecting millions worldwide. Traditional herbal medicine has garnered attention for its potential therapeutic benefits in preventing and managing these diseases. This review highlights the neuroprotective properties of six herbal plants such as Curcuma longa (Turmeric), Lavandula angustifolia (Lavender), Rosmarinus officinalis (Rosemary), Cardiospermum halicacabum (Balloon Vine), Careya arborea (Wild Guava), and Withania somnifera (Ashwagandha). These plants exhibit antioxidant, anti-inflammatory, and anti-apoptotic activities, inhibiting neurodegeneration and promoting neuronal survival. Their bioactive compounds, such as curcumin, linalool, and withanolides, demonstrate potential in preventing cognitive decline, neuroinflammation, and oxidative stress. This review provides an overview of some popular neuroprotective plants and their therapeutic roles in managing NDs, highlighting their pharmacological properties, mechanisms of action, and the current understanding of their efficacy.
Author: Shravani Dhanve*, Dipali Patil, Tanvi Bhosale, Mayuri Bhadalekar, Nilesh Chougule
Language: English
Field: Medicine
Open Access status: green
OpenAlex ID: W6911950746
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