Work

Synthesis of 3-(substitutedthiocarbamide)-aniline derivatives from di-tert-butyl dicarbonate (BoC) protected 3-chloroaniline

Year: 2024

Type: article

Abstract: Synthesis of substituted thiocarbamide derivatives is important in the fields of medicinal, agricultural, chemical, and pharmaceutical. Thiocarbamides are commonly utilized as starting materials for several organic synthetic processes and have been studied in search for easy and effective methods of chemical synthesis. In the existing research work, 3-chloroaniline was protected by a di-tert-butyl dicarbonate (BoC) protecting agent. Substituted thiocarbamide derivatives were synthesized using condensation of various substituted thioureas with amino group-protected 3-chloroaniline. The structures of all compounds of 3(substitutedthiocarbamido)-aniline were characterized by 1H-NMR, 13C-NMR, FT-IR, LCMS and CHNS elemental analysis.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.14709140

Authors: P. L. Harale, M. E. Shelke, D.T. Tayade, A. R. Kurhe

Institution: Government Vidarbha Institute of Science and Humanities

Language: English

Topic: Synthesis and Reactivity of Sulfur-Containing Compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

OpenAlex ID: W6911957142

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