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Personalized Surgical Management of Craniosynostosis in Children Using Advanced Msct Morphometry and Risk Stratification Models

Year: 2025

Type: article

Abstract: This study evaluates the effectiveness of a personalized approach to surgical treatment of craniosynostosis using enhanced MSCT morphometric protocols and risk stratification. A total of 120 pediatric patients aged 2 to 24 months were examined. Morphometric algorithms based on 14 key cranial parameters enabled precise classification of craniosynostosis types. Risk models identified high-risk patients with a preoperative neurological deficit rate of 18.7%. Radiation dose optimization led to a 35% dose reduction (average CTDIvol: 11.4 mGy). Surgical outcomes improved significantly with this approach, showing a 91.7% rate of excellent cosmetic results and a neurological improvement rate of 85% after 12 months.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.15261160

Author: Nazarova, L.A.

Language: English

Topic: Craniofacial Disorders and Treatments

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6912080592

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