Dubin Johnson Syndrome and the Enigma Surrounding Conjugated Hyperbilirubinemia in Pregnancy: A Case Report
Year: 2024
Type: article
Abstract: 1.1. Aim and Background: Jaundice in pregnancy is an uncommon condition. The aim is to diagnose a rare congenital hepatic disorder- Dubin Johnson Syndrome and elucidate an algorithm to arrive at it thus sensitizing the readers to unconventional diagnoses encountered while dealing with a case of jaundice in pregnancy. 1.2. Case Description: We present the case of a 27-year-old antenatal patient with unexplained conjugated hyperbilirubinemia exacerbating with every pregnancy in whom a set of comprehensive albeit feasible clinical tests helped to conclusively settle at the diagnosis of DJS. 1.3. Conclusion: More often benign than not, DJS is a rare entity with no risk of fibrosis progression, cirrhosis or adverse perinatal outcomes. 1.4. Clinical Significance: It is imperative to diagnose DJS not only to differentiate it from other pre-existing or concurrent hepatic disorders in pregnancy considerably impacting management strategies and foetal-maternal outcomes but also to reassure the patient of its benign course, an essential element of good clinical practice.
Author: Shah DR1, Dwivedi JS1*, Nimbkar AR1 and Mali KA1
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W6912105694
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