Formulation And Evaluation of Combination Tablet of Chia Seeds and Flaxseeds for Laxative Purpose
Year: 2025
Type: article
Abstract: Constipation is a widespread digestive issue that impacts a significant portion of the global population. This research focused on the formulation and assessment of a plant-based laxative tablet made from chia seed and flaxseed powders. Leveraging the gel-forming ability of chia and the rich dietary fiber content in flaxseeds, various formulations were prepared with different chia-to-flaxseed ratios. The tablets were evaluated for key physical parameters, including hardness, friability, and disintegration time. Laxative potential was tested using a rat model with induced constipation. Results indicated a marked improvement in stool output and frequency, especially in the batch with a 1:2 ratio of chia to flaxseed, which showed the most promising results due to the synergistic interaction of both ingredients. The tablets remained stable during testing and posed no safety concerns. These findings support the potential of this herbal formulation as a safe and effective natural solution for constipation, with scope for further clinical research.
Author: Janvi Joshi*, Aditi Tikait, Dr. Swati Deshmukh, Gauri Mankar
Language: English
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W6912110181
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