Work

Genome-Wide Crossover Analysis Identification of Shared Genetic Effect Site between Frailty and Multiple Psychiatric Disorders

Year: 2025

Type: article

Abstract: Additional file 2: Table S1. Data sources. Table S2. Genetic correlation analysis conducted by LDSC and HDL. Table S3. Identification of polymorphic risk SNP loci by using PLACO. Table S4. ANNOVAR category annotates leader SNP. Table S5. Colocalization analy sis. Table S6. Shared pleiotropic loci among different trait pairs. Table S7. S-LDSC tissue specific. Table S8. Identification of significant pleio-tropic genes by using MAGMA. Table S9. MAGMA Gene-set analysis. Table S10. MAGMA tissue-specific analysis. Table S11. European population drug targets. Table S12. Drug Target Annotation. Table S13. Multi-trait colocalization analysis highlighted key role of immune cells (PP>0.7).

Source: Machine Learning

DOI: 10.5281/zenodo.15449032

Author: Zhijun Tian, Yudan Zhou, Feng Mei, Ao Shen, Huijia Luo, Duoer Mei, Hong Guo

Institution: Shenyang Medical College

Language: English

Topic: Genetic Associations and Epidemiology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,290