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Assessment of Endothelial Dysfunction Biomarkers (et-1 and Enos) in the Context of Overweight and Arterial Hypertension

Year: 2025
Type: article
Abstract: This study evaluated the levels of molecular biomarkers of endothelial dysfunction − endothelin-1 (ET-1) and endothelial nitric oxide synthase (eNOS) − in individuals with excess body weight and arterial hypertension. Clinical and laboratory assessments demonstrated that elevated ET-1 levels and decreased eNOS concentrations indicate disruption of endothelial balance and progression of the pathological process. A comprehensive analysis of these biomarkers may serve as a valuable diagnostic tool for early detection of endothelial dysfunction and evaluation of metabolic risk factors.
Authors: U.I. Usmanova, U.Kh. Musashaykhov, D.A. Nabiyeva
Language: English
Subfield: Physiology
Field: Medicine
Open Access status: green
OpenAlex ID: W6912197109
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