Work

Q-well-posedness of an A

Year: 2024

Type: article

Abstract: In this work, we consider a Becker-Döring-like mathematical interaction model between Aβ-monomers and Aβ proto-oligomers playing an important role in Alzheimer’s disease. In this context, the clustering process where two or more Aβ-monomers spontaneously aggregate and form a seed of proto-oligomers is highlighted. We prove the quadratic well-posedness [4] of the problem associated with the estimation of clustering rate μ from measured data at different times.

Source: Springer Link (Chiba Institute of Technology)

DOI: 10.1051/mmnp/2023028/pdf

Authors: Cheikh Gueye, Sorin I. Ciuperca, Laurent Pujo-Menjouet, Léon Matar Tine

Institutions: Lyon 1 Université, Centre National de la Recherche Scientifique, Institut national de recherche en sciences et technologies du numérique, Institut Camille Jordan, Cheikh Anta Diop University

Language: English

Topic: Alzheimer's disease research and treatments

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

Open Access status: green

Funder: Agence Nationale de la Recherche

Award: Impact of replication and structural diversification of prions on their cerebral dissemination