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Meniere’s disease: an inner ear disease caused by multiple factors

Year: 2025

Type: article

Abstract: Meniere’s disease (MD) is an inner ear disorder characterized by recurrent vertigo, fluctuating hearing loss, tinnitus, and aural fullness. The pathogenesis of MD remains unclear but is closely associated with endolymphatic hydrops (EH), immune dysregulation, genetic predisposition, vascular dysfunction, and viral infection. This review summarizes recent research advances of MD pathogenesis, suggesting that MD may be a heterogeneous condition with distinct subtypes driven by different mechanisms. Future studies should integrate multi-omics analyses and animal models to elucidate its molecular pathways.

Source: DOAJ (DOAJ: Directory of Open Access Journals)

DOI: 10.12025/j.issn.1008-6358.2025.20250369

Authors: Huaili JIANG, Xinsheng HUANG

Institutions: Fudan University, Zhongshan Hospital

Language: English

Topic: Vestibular and auditory disorders

Subfield: Neurology

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6922072909

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