In Vitro Hypoglycemic, Hypolipidemic Activities and Antioxidant Capacity of Dark Tea and Pericarpium Citri Reticulatae Extract with Pericarpium Citri Reticulatae Volatile Oil
Year: 2025
Type: article
Abstract: Objective: Exploring the in vitro hypoglycemic, hypolipidemic and antioxidant activity of Pericarpium Citri Reticulatae volatile oil and dark tea/Pericarpium Citri Reticulatae extract. Methods: The volatile oil components of Pericarpium Citri Reticulatae were analyzed by gas chromatography-mass spectrometry (GC-MS), and then the effects of Pericarpium Citri Reticulatae, dark tea, dark tea with Pericarpium Citri Reticulatae extract and Pericarpium Citri Reticulatae volatile oil on in vitro α-glucosidase, pancreatic α-amylase, pancreatic lipase activity and the DPPH and ABTS+ free radicals scavenging capacity were studied with acarbose, orlistat and vitamin C (VC) as controls. Results: Limonene was the main component of Pericarpium Citri Reticulatae volatile oil, accounting for 62.89% of the total relative content. The inhibition rate of α-glucosidase of dark tea with Pericarpium Citri Reticulatae+volatile oil group (0.1 mg/mL) was 83.38%±1.82%, and the IC50 value was: acarbose<dark tea<dark tea with Pericarpium Citri Reticulatae+volatile oil<dark tea with Pericarpium Citri Reticulatae
Authors: Zhitao PAN, Tingyu HUA, Xiaoyun WANG, Yi SHEN, Xunzhen ZHANG, Shaotong HUANG, Hanying DUAN, Chao WANG
Institution: Jinan University
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W6923170912
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