Work

Mitochondrial Regulation of T-cell Antitumor Immunity and Aging

Year: 2024

Type: article

Abstract: This study aims to investigate the role of mitochondrial dysfunction in T-cell immunity, focusing on its effects on tumor control, aging processes, and systemic immune regulation. Using an inducible mouse model with reversible mitochondrial DNA depletion, we will explore metabolic pathways, immune cell functions, and therapeutic interventions.

Source: Bundesinstitut für Risikobewertung Fachgruppe ZEBET - Datenbank und Informationsbeschaffung Abteilung Experimentelle Toxikologie und ZEBET

DOI: 10.17590/asr.0000376

Author: Federal Institute For Risk Assessment

Language: English

Topic: Mitochondrial Function and Pathology

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6925366473

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