Work

A custom CRISPR-Cas9 library screen to study the impact of single genes on neutrophil function

Year: 2024

Type: conference-paper

Abstract: Introduction: Neutrophils are essential mediators of host defense and pathologic inflammation. We recently described that neutrophils display high plasticity, enabling them to acquire both tissue as well as disease-specific signatures. Now, new approaches are needed to mechanistically study the role [for full text, please go to the a.m. URL]

Source: German Medical Science (German Research Foundation)

DOI: 10.3205/24dgrh019

Authors: Junker, Niklas Rudolf, Exner, Tarik, Zhang, Liang, Anoshkin, Kirill, Osmanusta, Cemil Görkem, Leonhardt, Sophie Elisabeth, Schett, Georg, Lorenz, Hanns-Martin, Wabnitz, Guido, Grieshaber-Bouyer, Ricardo

Institutions: University Hospital Heidelberg, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsklinikum Erlangen

Language: English

Topic: Neutrophil, Myeloperoxidase and Oxidative Mechanisms

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6927678615

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