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Low pregnenolone levels/-deficiency in patients with rheumatoid arthritis and fibromyalgia syndrome – an interesting biomarker and potential therapeutic target

Year: 2024

Type: conference-paper

Abstract: Introduction: We tested the hypothesis that decreased pregnenolone levels are common in patients with rheumatoid arthritis (RA) and fibromyalgia (FMS). Pregnenolone (PR) synthesis is the first and rate-limiting step in steroidogenesis, in which cholesterol is converted in mitochondria to pregnenolone, [for full text, please go to the a.m. URL]

Source: German Medical Science (German Research Foundation)

DOI: 10.3205/24dgrh169

Authors: Schütz, Uwe, Maier-Janson, Walter

Language: English

Topic: Adrenal Hormones and Disorders

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6927706476

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