“formulation, Characterization and in Vitro Evaluation of Betulinic Acid-loaded Lipid Nanocarriers for Enhanced Bioavailability and Sustained Release in Lung Cancer Therapy”
Year: 2025
Type: article
Abstract: Betulinic Acid, a bioactive compound with significant anticancer potential, suffers from poor solubility and low bioavailability, limiting its therapeutic efficacy. This study aimed to develop Betulinic Acid-loaded lipid nanocarriers (BALNCs) to enhance drug solubility, bioaccessibility, and controlled release. With particle diameters between 42 and 44 nm, a polydispersity index (PDI) of approximately 0.26, and a zeta potential of approximately 20 mV, the nanocarriers were effectively synthesised and characterised, guaranteeing stability.
Source: Cuestiones de Fisioterapia
DOI: 10.48047/jr94mm57
Authors: Namrata Sanjay Mane, Pankaj Mohan Pimpalshende, Jeevanandham Somasundaram, Muthukumaran Mylasalam, Indu Mittal, V. Saravanan, Renuka D Kadu, Rutuja Dattatray Chougale
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: hybrid
OpenAlex ID: W6929092572