Recent Innovations in Lipid-lowering Therapies
Year: 2024
Type: article
Abstract: Dyslipidemia is a major risk factor for atherosclerotic cardiovascular diseases. Recent advancements in lipid-lowering therapies have seen progress with statins, cholesterol absorption inhibitors, PCSK9 inhibitors, and omega-3 fatty acids becoming widely utilized. Emerging new lipid-lowering drugs, including angiopoietin-like protein 3 (ANGPTL3) inhibitors, apolipoprotein C3 inhibitors, monoclonal antibodies, antisense oligonucleotides (ASOs), small interfering RNA (siRNA), and cholesterol vaccines, have diversified the therapeutic landscape, showing promising efficacy. This review explores the development and application of these lipidlowering drugs, offering new insights for therapeutic strategies.
Authors: Xin Hu, Xiaoming Wang
Institutions: Xijing Hospital, Air Force Medical University
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W6929132318
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