A systematic review and meta-analysis of dental implants in patients with diabetes mellitus
Year: 2024
Type: review
Abstract: This review aimed to assess the effects of diabetes mellitus on dental implant failure rates and marginal bone loss (MBL). An electronic search was conducted across three databases, supplemented by a manual search of relevant journals. Meta-analyses and meta-regressions were performed to examine how the odds ratio (OR) and MBL were influenced by follow-up duration. A total of 89 studies were included in the review, encompassing 5,510 implants in diabetic patients and 62,780 in non-diabetic patients. Pairwise meta-analysis revealed a higher failure risk for implants in diabetic patients compared to non-diabetic patients (OR 1.777, p < 0.001). Implant failure was significantly more frequent in type 1 diabetes patients than in type 2 (OR 4.477, p = 0.032). Statistically significant differences in implant failure rates were observed between the maxilla and mandible, with significance only in the maxilla. The mean difference (MD) in MBL between diabetic and non-diabetic patients was 0.776 mm (p = 0.027), with an estimated MBL MD increase of 0.032 mm per additional month of follow-up (p < 0.001). Additionally, there was an estimated OR decrease of 0.007 for each extra month of follow-up (p = 0.048). In conclusion, dental implants in diabetic patients showed a 77.7% higher failure risk compared to those in non-diabetic patients.
Author: Zakir Saparbayev
Institution: Alfred University
Language: English
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W6930206037
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