Prevalence of Polycystic Ovary Syndrome (PCOS) in Adolescent Girls with Vague Symptoms Post-Menarche: A Cross-Sectional Study in a Gynecology Outpatient Clinic
Year: 2024
Type: article
Abstract: ABSTRACT: Background: Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder that often presents with vague symptoms post-menarche. Early diagnosis is crucial to prevent long-term complications. Objective: This study aimed to determine the prevalence of PCOS in adolescent girls with vague post-menarche symptoms and to assess the relationship between obesity and PCOS. Methods: A cross-sectional study was conducted over 12 months at a tertiary care hospital. A total of 100 adolescent girls (aged 13-19 years) with symptoms such as irregular periods, acne, and hirsutism were included. PCOS was diagnosed using the Rotterdam criteria. Data collection included clinical evaluations (BMI, hyperandrogenism), laboratory tests (serum testosterone, LH/FSH ratio), and pelvic ultrasound. Statistical analyses were performed, with significance set at p < 0.05. Results: PCOS was diagnosed in 42% of participants. Menstrual irregularities (85%), acne (66%), and hirsutism (54%) were the most common symptoms. Obesity was strongly associated with PCOS, with 72.2% of overweight/obese participants diagnosed compared to 25% of normal-weight participants (p < 0.001). Elevated serum testosterone (64.3%) and abnormal LH/FSH ratios (76.2%) were prevalent in PCOS cases. Conclusion: PCOS was highly prevalent in symptomatic adolescents. Early screening, particularly in overweight girls, is essential to prevent complications. Further research is needed to explore long-term outcomes. Keywords: Polycystic Ovary Syndrome, PCOS, adolescent girls, prevalence, cross-sectional study, vague symptoms, post-menarche, gynecology outpatient clinic.
Author: Dr. Reshma Kaiser Rafi, Dr. Sara Tahir Dr. Nilufa Easmin, Dr. Shafaq Rubab Dr. Khushboo Kumari, Dr. Ali Farooq Dr. Shurouq Ashraf Tabash Dr. Ebube Onyedika Molokwu Dr. Amber Fazal Elahi
Language: English
Subfield: Reproductive Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W6930383757
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